R406 free base

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TargetMol
Product Code: TAR-T2467
Supplier: TargetMol
CodeSizePrice
TAR-T2467-1mg1mg£102.00
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TAR-T2467-5mg5mg£122.00
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TAR-T2467-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T2467-10mg10mg£149.00
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TAR-T2467-25mg25mg£229.00
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TAR-T2467-50mg50mg£356.00
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TAR-T2467-100mg100mg£523.00
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TAR-T2467-500mg500mg£1,018.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
R406 (free base) is a potent Syk inhibitor.
CAS:
841290-80-0
Formula:
C22H23FN6O5
Molecular Weight:
470.461
Pathway:
Apoptosis; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9931
SMILES:
COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)cc(OC)c1OC
Target:
Apoptosis; FLT; Syk

References

1. Braselmann S, et al. J Pharmacol Exp Ther, 2006, 319(3), 998-1008. 2. Chen L, et al. Blood, 2008, 111(4), 2230-2237. 3. Fruchon S, et al. Leukemia, 2011, 1-11.