LB42708

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TargetMol
Product Code: TAR-T2678
Supplier: TargetMol
CodeSizePrice
TAR-T2678-1mg1mg£104.00
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TAR-T2678-2mg2mg£117.00
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TAR-T2678-5mg5mg£141.00
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TAR-T2678-1mL1 mL * 10 mM (in DMSO)£189.00
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TAR-T2678-10mg10mg£189.00
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TAR-T2678-25mg25mg£305.00
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TAR-T2678-50mg50mg£421.00
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TAR-T2678-100mg100mg£561.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
CAS:
226929-39-1
Formula:
C30H27BrN4O2
Molecular Weight:
555.476
Pathway:
Metabolism
Purity:
0.98
SMILES:
Brc1ccc(Cn2cncc2Cn2cc(C(=O)N3CCOCC3)c(c2)-c2cccc3ccccc23)cc1
Target:
Transferase

References

1. Na HJ, et al. J Immunol. 2004, 173(2), 1276-1283. 2. Kim HS, et al. Toxicol Appl Pharmacol. 2006, 215(3), 317-329. 3. Kim CK, et al. Mol Pharmacol. 2010, 78(1), 142-150