PF-1355

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TargetMol
Product Code: TAR-T3511
Supplier: TargetMol
CodeSizePrice
TAR-T3511-1mg1mg£95.00
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TAR-T3511-2mg2mg£106.00
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TAR-T3511-5mg5mg£128.00
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TAR-T3511-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T3511-10mg10mg£168.00
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TAR-T3511-25mg25mg£230.00
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TAR-T3511-50mg50mg£369.00
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TAR-T3511-100mg100mg£502.00
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TAR-T3511-200mg200mg£687.00
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TAR-T3511-500mg500mg£994.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
CAS:
1435467-38-1
Formula:
C14H15N3O4S
Molecular Weight:
321.35
Pathway:
Metabolism
Purity:
0.9977
SMILES:
O=C1C=C(C=2C=C(OC)C=CC2OC)N(C(=S)N1)CC(=O)N
Target:
Glutathione Peroxidase

References

Zheng W, et al. PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritis. J Pharmacol Exp Ther. 2015 May;353(2):288-98