SCH900776 (S-isomer)

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TargetMol
Product Code: TAR-T3700
Supplier: TargetMol
CodeSizePrice
TAR-T3700-1mg1mg£107.00
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TAR-T3700-2mg2mg£122.00
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TAR-T3700-5mg5mg£148.00
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TAR-T3700-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T3700-10mg10mg£197.00
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TAR-T3700-25mg25mg£294.00
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TAR-T3700-50mg50mg£430.00
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TAR-T3700-100mg100mg£600.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
CAS:
891494-64-7
Formula:
C15H18BrN7
Molecular Weight:
376.262
Pathway:
Cell Cycle/Checkpoint
Purity:
0.9995
SMILES:
Cn1cc(cn1)-c1cnn2c(N)c(Br)c(nc12)[C@H]1CCCNC1
Target:
Chk; CDK

References

Montano R, et al. Mol Y Ther. 2012 Feb;11(2):427-38. Guzi TJ, et al. Mol Y Ther, 2011, 10(4), 591-602. Thompson R, et al. PLoS One. 2012;7(8):e44021.