XMD16-5

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TargetMol
Product Code: TAR-T3710
Supplier: TargetMol
CodeSizePrice
TAR-T3710-1mg1mg£100.00
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TAR-T3710-2mg2mg£111.00
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TAR-T3710-1mL1 mL * 10 mM (in DMSO)£144.00
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TAR-T3710-5mg5mg£144.00
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TAR-T3710-10mg10mg£189.00
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TAR-T3710-25mg25mg£261.00
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Quantity:
TAR-T3710-50mg50mg£422.00
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TAR-T3710-100mg100mg£591.00
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TAR-T3710-500mg500mg£1,179.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is disrupted in breast, prostate and gastrointestinal tumors.
CAS:
1345098-78-3
Formula:
C23H24N6O2
Molecular Weight:
416.485
Pathway:
Proteases/Proteasome; Metabolism; DNA Damage/DNA Repair
Purity:
0.9853
SMILES:
CN1c2ccccc2C(=O)Nc2cnc(Nc3ccc(cc3)N3CCC(O)CC3)nc12
Target:
Tyrosinase; PPAR

References

Maxson JE, et al. Cancer Res. 2016, 76(1):127-38.