Acebilustat

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TargetMol
Product Code: TAR-T3715
Supplier: TargetMol
CodeSizePrice
TAR-T3715-1mg1mg£101.00
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TAR-T3715-2mg2mg£114.00
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TAR-T3715-5mg5mg£142.00
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TAR-T3715-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T3715-10mg10mg£168.00
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TAR-T3715-25mg25mg£269.00
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TAR-T3715-50mg50mg£386.00
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TAR-T3715-100mg100mg£540.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Acebilustat (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.
CAS:
943764-99-6
Formula:
C29H27N3O4
Molecular Weight:
481.552
Pathway:
Metabolism; Immunology/Inflammation
Purity:
0.9947
SMILES:
OC(=O)c1ccc(CN2C[C@@H]3C[C@H]2CN3Cc2ccc(Oc3ccc(cc3)-c3ncco3)cc2)cc1
Target:
Aminopeptidase; LTR

References

Elborn JS, et al. Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction. Clin Transl Sci. 2016 Oct 28. Elborn JS, et al. Phase 1 Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis. Clin Transl Sci. 2016 Nov 2.