KBC-007
Code | Size | Price |
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TAR-T38008-2mg | 2mg | £1,193.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Documents
Further Information
Bioactivity:
KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the survival rate of mice immunized with the inactivated influenza A virus A/PR/8/34 in a model of influenza infection.
CAS:
1037297-61-2
Formula:
C46H92N2O9
Molecular Weight:
817.2
Purity:
0.98
SMILES:
OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H]([C@H](O)[C@H](O)CCCCCCCCCCCCCC)NC(CCCCCCCN(CCCCCCC)CCCCCCC)=O)O1