ICA-069673

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TargetMol
Product Code: TAR-T3959
Supplier: TargetMol
CodeSizePrice
TAR-T3959-2mg2mg£103.00
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TAR-T3959-5mg5mg£124.00
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TAR-T3959-1mL1 mL * 10 mM (in DMSO)£130.00
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TAR-T3959-10mg10mg£164.00
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TAR-T3959-25mg25mg£277.00
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TAR-T3959-50mg50mg£438.00
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TAR-T3959-100mg100mg£616.00
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TAR-T3959-500mg500mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
CAS:
582323-16-8
Formula:
C11H6ClF2N3O
Molecular Weight:
269.64
Pathway:
Membrane transporter/Ion channel
Purity:
0.9966
SMILES:
Fc1ccc(cc1F)C(=O)Nc1cnc(Cl)nc1
Target:
Potassium Channel

References

Wickenden AD, et al. N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. Mol Pharmacol. 2008 Mar;73(3):977-86. Epub 2007 Dec 18. Wang AW, et al. Sequence determinants of subtype-specific actions of KCNQ channel openers. J Physiol. 2017 Feb 1;595(3):663-676.