TMP195

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TargetMol
Product Code: TAR-T3983
Supplier: TargetMol
CodeSizePrice
TAR-T3983-2mg2mg£124.00
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TAR-T3983-1mL1 mL * 10 mM (in DMSO)£160.00
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Quantity:
TAR-T3983-5mg5mg£160.00
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Quantity:
TAR-T3983-10mg10mg£222.00
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Quantity:
TAR-T3983-25mg25mg£375.00
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Quantity:
TAR-T3983-50mg50mg£436.00
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Quantity:
TAR-T3983-100mg100mg£608.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TMP195 is a selective class IIa histone deacetylase (HDAC) inhibitor.
CAS:
1314891-22-9
Formula:
C23H19F3N4O3
Molecular Weight:
456.425
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9892
SMILES:
CC(C)(CNC(=O)c1cccc(c1)-c1noc(n1)C(F)(F)F)c1coc(n1)-c1ccccc1
Target:
HDAC

References

Yue Y, Li F, Li Y, et al. Biomimetic Nanoparticles Carrying a Repolarization Agent of Tumor-Associated Macrophages for Remodeling of the Inflammatory Microenvironment Following Photothermal Therapy. ACS nano. 2021, 15(9): 15166-15179. Lobera M., et al. Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group. Nat Chem Biol. 2013 May;9(5):319-25.