Norisoboldine
| Code | Size | Price |
|---|
| TAR-T5S1895-5mg | 5mg | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
1. Norisoboldine might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisoboldine inhibits the macrophage activation and the resultant production of pro-inflammatory cytokines via down-regulating the activation of MAPKs signaling pathways rather than NF-κB.
CAS:
23599-69-1
Formula:
C18H19NO4
Molecular Weight:
313.353
Pathway:
Neuroscience; GPCR/G Protein; MAPK
Purity:
0.9864
SMILES:
COc1cc-2c(C[C@@H]3NCCc4cc(OC)c(O)c-2c34)cc1O
Target:
MAPK; Adenosine Receptor
References
Tong B , Dou Y , Wang T , et al. Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues.[J]. Toxicology & Applied Pharmacology, 2015, 282(1):90-99.