V-0219
Code | Size | Price |
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TAR-T60047-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60047-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.
CAS:
878453-71-5
Formula:
C20H25F3N4O2
Molecular Weight:
410.43
Pathway:
GPCR/G Protein
Purity:
1
SMILES:
FC(F)(F)C=1C=CC(=CC1)C2=NOC(=N2)CN3CCCC(C3)CN4CCOCC4
Target:
Glucagon Receptor
References
Decara JM, et al. Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity". J Med Chem. 2022 Apr 14;65(7):5449-5461.