Selinexor (KPT-330)
Code | Size | Price |
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TAR-T6106-2mg | 2mg | £102.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6106-5mg | 5mg | £130.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6106-25mg | 25mg | £296.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6106-50mg | 50mg | £409.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6106-100mg | 100mg | £457.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity.
CAS:
1393477-72-9
Formula:
C17H11F6N7O
Molecular Weight:
443.31
Pathway:
Membrane transporter/Ion channel
Purity:
0.9985
SMILES:
c1cnc(cn1)NNC(=O)/C=C
1cnc(n1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Target:
CRM1
References
Han Y, Hu A, Qu Y, et al.Covalent targeting the LAS1-NOL9 axis for selective treatment in NPM1 mutant acute myeloid leukemia.Pharmacological Research.2023: 106700.
Tai YT, et al. Leukemia. 2014, 28(1), 155-165.
Etchin J, et al. Br J Haematol. 2013, 161(1), 117-127.