TW-37

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TargetMol
Product Code: TAR-T6281
Supplier: TargetMol
CodeSizePrice
TAR-T6281-1mg1mg£98.00
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TAR-T6281-2mg2mg£109.00
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TAR-T6281-5mg5mg£121.00
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TAR-T6281-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T6281-10mg10mg£163.00
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TAR-T6281-25mg25mg£251.00
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TAR-T6281-50mg50mg£369.00
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TAR-T6281-100mg100mg£511.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).
CAS:
877877-35-5
Formula:
C33H35NO6S
Molecular Weight:
573.7
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CC(C)c1ccccc1Cc1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)c2ccccc2C(C)(C)C)c(O)c(O)c1O
Target:
BCL

References

Verhaegen M, et al. Cancer Res. 2006, 66(23), 11348-11359. Mohammad RM, et al. Clin Cancer Res, 2007, 13(7), 2226-2235. Zeitlin BD, et al. Cancer Res, 2006, 66(17), 8698-8706.