Bazedoxifene hydrochloride
Code | Size | Price |
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TAR-T6404-2mg | 2mg | £133.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T6404-5mg | 5mg | £183.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6404-1mL | 1 mL * 10 mM (in DMSO) | £273.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6404-10mg | 10mg | £273.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6404-25mg | 25mg | £387.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6404-50mg | 50mg | £640.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively.
CAS:
198480-56-7
Formula:
C30H35ClN2O3
Molecular Weight:
507.07
Pathway:
Endocrinology/Hormones
Purity:
0.98
SMILES:
Cl.Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc12
Target:
Estrogen Receptor/ERR; Estrogen/progestogen Receptor
References
Diane M Biskobing, et al. Clin Interv Aging. 2007 Sep; 2(3): 299?303.
Li J, Yu F, Guo H, et al. Crystal structure of plant PLD?1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D[J]. Cell Research. 2020, 30(1): 61-69.
Miller CP, et al. J Med Chem, 2001, 44(11), 1654-1657.
Komm BS, et al. Endocrinology, 2005, 146(9), 31999-42008.
Li J, Yu F, Guo H, et al. Crystal structure of plant PLD?1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D. Cell Research. 2020, 30(1): 61-69.