Hesperadin
Code | Size | Price |
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TAR-T6532-2mg | 2mg | £97.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6532-5mg | 5mg | £112.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6532-1mL | 1 mL * 10 mM (in DMSO) | £118.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6532-10mg | 10mg | £132.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6532-25mg | 25mg | £173.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6532-50mg | 50mg | £237.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo.
CAS:
422513-13-1
Formula:
C29H32N4O3S
Molecular Weight:
516.66
Pathway:
Microbiology/Virology; Cell Cycle/Checkpoint; Autophagy; Chromatin/Epigenetic
Purity:
0.9944
SMILES:
CCS(=O)(=O)Nc1ccc2NC(=O)C(=C(/Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)c2c1
Target:
Influenza Virus; Parasite; Aurora Kinase; Autophagy
References
Hauf S, et al. J Cell Biol, 2003, 161(2), 281-294.
Wang J, Yan X, Chen H, et al. Enhanced UV-B radiation affects AUR1 regulation of mitotic spindle morphology leading to aberrant mitosis. Plant Physiology and Biochemistry. 159: 160-170.
Jetton N, et al. Mol Microbiol, 2009, 72(2), 442-458.
Wang J, Yan X, Chen H, et al. Enhanced UV-B radiation affects AUR1 regulation of mitotic spindle morphology leading to aberrant mitosis[J]. Plant Physiology and Biochemistry. 159: 160-170.