Nelarabine

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TargetMol
Product Code: TAR-T6603
Supplier: TargetMol
CodeSizePrice
TAR-T6603-1mg1mg£99.00
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TAR-T6603-2mg2mg£112.00
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TAR-T6603-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T6603-5mg5mg£136.00
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TAR-T6603-10mg10mg£185.00
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TAR-T6603-25mg25mg£279.00
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TAR-T6603-50mg50mg£439.00
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TAR-T6603-100mg100mg£535.00
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TAR-T6603-500mg500mg£1,050.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Nelarabine is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
CAS:
121032-29-9
Formula:
C11H15N5O5
Molecular Weight:
297.27
Pathway:
DNA Damage/DNA Repair; Apoptosis; Cell Cycle/Checkpoint
Purity:
0.996
SMILES:
COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
Target:
Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis

References

Kline J, et al. Expert Opin Pharmacother. 2006, 7(13), 1791-1799. Beesley AH, et al. Br J Haematol. 2007, 137(2), 109-116. Berg SL, et al. Cancer Chemother Pharmacol. 2007, 59(6), 743-747. DeAngelo DJ, et al. Blood. 2007, 109(12), 5136-5142.