Nutlin-3b

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TargetMol
Product Code: TAR-T6614
Supplier: TargetMol
CodeSizePrice
TAR-T6614-1mg1mg£107.00
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TAR-T6614-2mg2mg£122.00
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TAR-T6614-5mg5mg£164.00
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TAR-T6614-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T6614-10mg10mg£232.00
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TAR-T6614-25mg25mg£329.00
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TAR-T6614-50mg50mg£458.00
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TAR-T6614-100mg100mg£626.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Nutlin-3b is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 μM), 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
CAS:
675576-97-3
Formula:
C30H30Cl2N4O4
Molecular Weight:
581.49
Pathway:
Apoptosis; Ubiquitination
Purity:
0.9883
SMILES:
COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
Target:
Mdm2; E1/E2/E3 Enzyme

References

Vassilev LT, et al. Science, 2004, 303(5659), 844-848.