SC75741

TargetMol
Product Code: TAR-T6661
Supplier: TargetMol
CodeSizePrice
TAR-T6661-1mg1mg£99.00
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TAR-T6661-5mg5mg£134.00
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TAR-T6661-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T6661-10mg10mg£182.00
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TAR-T6661-25mg25mg£269.00
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TAR-T6661-50mg50mg£454.00
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TAR-T6661-100mg100mg£624.00
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TAR-T6661-500mg500mg£1,259.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
SC75741 is a potent P65 inhibitor with IC50 of 200 nM
CAS:
913822-46-5
Formula:
C29H23N7O2S2
Molecular Weight:
565.67
Pathway:
Microbiology/Virology; NF-κb
Purity:
0.9944
SMILES:
O=C(Nc1nc2ccc(cc2[nH]1)C(=O)c1ccccc1)c1csc(n1)C1CCN(CC1)c1ncnc2ccsc12
Target:
Influenza Virus; NF-κB

References

Leban J, et al. Bioorg Med Chem Lett. 2007, 17(21), 5858-5862. Hu, Qiuhui, Hengjun Du, Gaoxing Ma, Fei Pei, Ning Ma, Biao Yuan, Paul A. Nakata, and Wenjian Yang. Purification, identification and functional characterization of an immunomodulatory protein from Pleurotus eryngii [J]. Food Funct. 2018 Jul 17;9(7):3764-3775. Ehrhardt C, et al. Cell Microbiol. 2013, 15(7), 1198-1211. Hu Q, Du H, Ma G, et al. Purification, identification and functional characterization of an immunomodulatory protein from Pleurotus eryngii. Food & Function. 2018, 9(7): 3764-3775 Zhou D, Yang S, Yan H, et al. SC75741, a novel c-Abl inhibitor, promotes the clearance of TDP25 aggregates via ATG5-dependent autophagy pathway. Frontiers in Pharmacology. 2021: 2891. Su J, Yin W, Huo M, et al.Induction of apoptosis in glioma cells by lycorine via reactive oxygen species generation and regulation of NF-?B pathways.Naunyn-Schmiedeberg's Archives of Pharmacology.2023: 1-9.