RS-127445

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TargetMol
Product Code: TAR-T6973
Supplier: TargetMol
CodeSizePrice
TAR-T6973-2mg2mg£103.00
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TAR-T6973-5mg5mg£111.00
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TAR-T6973-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T6973-10mg10mg£135.00
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TAR-T6973-25mg25mg£208.00
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TAR-T6973-50mg50mg£306.00
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TAR-T6973-100mg100mg£521.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
RS-127445 is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.
CAS:
199864-87-4
Formula:
C17H16FN3
Molecular Weight:
281.334
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9881
SMILES:
CC(C)c1cc(nc(N)n1)-c1ccc(F)c2ccccc12
Target:
5-HT Receptor

References

Ohashi-Doi K, et al. Neurogastroenterol Motil, 2010, 22(2),e69-e76. Douglas W Bonhaus, et al. Br J Pharmacol, 1999, 127(5), 1075-1082. Bassil AK, et al. Br J Pharmacol, 2009, 158(1), 252-258.