CID-1067700

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TargetMol
Product Code: TAR-T7558
Supplier: TargetMol
CodeSizePrice
TAR-T7558-1mg1mg£95.00
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TAR-T7558-2mg2mg£106.00
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TAR-T7558-5mg5mg£125.00
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TAR-T7558-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T7558-10mg10mg£161.00
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TAR-T7558-25mg25mg£230.00
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TAR-T7558-50mg50mg£279.00
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TAR-T7558-100mg100mg£340.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases?Rab7 with a Ki of 13 nM).
CAS:
314042-01-8
Formula:
C18H18N2O4S2
Molecular Weight:
390.47
Pathway:
GPCR/G Protein; MAPK
Purity:
0.98
SMILES:
CC1(C)Cc2c(CO1)sc(NC(=S)NC(=O)c1ccccc1)c2C(O)=O
Target:
Ras

References

Yuan, Yang, Yong-ming, et al. CID 1067700, a late endosome GTPase Rab7 receptor antagonist, attenuates brain atrophy, improves neurologic deficits and inhibits reactive astrogliosis in rat ischemic stroke[J]. 2019(6):724-736. Agola J O , Hong L , Surviladze Z , et al. A Competitive Nucleotide Binding Inhibitor: ,?In Vitro , Characterization of Rab7 GTPase Inhibition[J]. ACS Chemical Biology, 2012, 7(6):1095-1108.