Autogramin-2

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TargetMol
Product Code: TAR-T9013
Supplier: TargetMol
CodeSizePrice
TAR-T9013-1mg1mg£98.00
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TAR-T9013-2mg2mg£109.00
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TAR-T9013-5mg5mg£135.00
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TAR-T9013-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T9013-10mg10mg£168.00
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TAR-T9013-25mg25mg£254.00
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TAR-T9013-50mg50mg£369.00
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TAR-T9013-100mg100mg£523.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Autogramin-2 potently inhibits?autophagy?induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
CAS:
2375541-45-8
Formula:
C21H27N3O4S
Molecular Weight:
417.52
Pathway:
Autophagy
Purity:
0.9625
SMILES:
CC(C)Oc1ccc(cc1)C(=O)Nc1nc2CCN(Cc2s1)C(=O)OC(C)(C)C
Target:
Autophagy

References

Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.