Meclofenamate sodium hydrate

TargetMol
Product Code: TAR-T0260L
Supplier: TargetMol
CodeSizePrice
TAR-T0260L-5mg5mg£850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Meclofenamate sodium is a potent non-steroidal anti-inflammatory agent, which can specifically inhibit chemokine-induced human polymorphonuclear leukocyte function: chemotaxis, degranulation, and superoxide anion free radical production.
CAS:
67254-91-5
Formula:
C14H12Cl2NNaO3
Molecular Weight:
336.14
Purity:
0.98
SMILES:
O.[Na+].Cc1ccc(Cl)c(Nc2ccccc2C([O-])=O)c1Cl

References

1. Ghosh R, Hwang SM, Cui Z, Gilda JE, Gomes AV. Different effects of the nonsteroidal anti-inflammatory drugs meclofenamate sodium and naproxen sodium on proteasome activity in cardiac cells. J Mol Cell Cardiol. 2016 May;94:131-44. doi: 10.1016/j.yjmcc.2016.03.016. Epub 2016 Apr 3. PubMed PMID: 27049794. 2. Hersh EV, Cooper S, Betts N, Wedell D, MacAfee K, Quinn P, Lamp C, Gaston G, Bergman S, Henry E. Single dose and multidose analgesic study of ibuprofen and meclofenamate sodium after third molar surgery. Oral Surg Oral Med Oral Pathol. 1993 Dec;76(6):680-7. PubMed PMID: 8284070. 3. Reddy MS, Palcanis KG, Barnett ML, Haigh S, Charles CH, Jeffcoat MK. Efficacy of meclofenamate sodium (Meclomen) in the treatment of rapidly progressive periodontitis. J Clin Periodontol. 1993 Oct;20(9):635-40. PubMed PMID: 8227450. 4. Mongini F, Bona G, Garnero M, Gioria A. Efficacy of meclofenamate sodium versus placebo in headache and craniofacial pain. Headache. 1993 Jan;33(1):22-8. PubMed PMID: 8436494.