AKT-IN-2
Code | Size | Price |
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TAR-T10274-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
CAS:
1295514-91-8
Formula:
C25H34F3N7O
Molecular Weight:
505.59
Pathway:
Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
C[C@@H]1CC(=O)Nc2ncnc(N3CCC(CC3)c3nc(CCC(F)(F)F)cn3CCN3CCCC3)c12
Target:
Akt
References
1. Parthasarathy S, et al. Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1887-1891.