Lovastatin
Code | Size | Price |
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TAR-T1207-1mL | 1 mL * 10 mM (in DMSO) | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1207-50mg | 50mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1207-100mg | 100mg | £124.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
CAS:
75330-75-5
Formula:
C24H36O5
Molecular Weight:
404.547
Pathway:
Metabolism; Apoptosis; Cell Cycle/Checkpoint; Autophagy
Purity:
0.9972
SMILES:
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
Target:
Ferroptosis; HMG-CoA Reductase; Autophagy
References
1. Pahan K, et al. J Clin Invest, 1997, 100(11), 2671-2679.
2. Keyomarsi K, et al. Cancer Res, 1991, 51(13), 3602-3609.
3. Tobert JA, et al. Nat Rev Drug Discov, 2003, 2(7), 517-526.
4. Rao S, et al. Proc Natl Acad Sci U S A, 1999, 96(14), 7797-7802.
5. Jak?bisiak M, et al. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3628-32.
6. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks[J]. Chemical Science. 2020, 11(7): 1775-1797.