PF-06952229

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TargetMol
Product Code: TAR-T12433
Supplier: TargetMol
CodeSizePrice
TAR-T12433-1mg1mg£164.00
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TAR-T12433-5mg5mg£303.00
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TAR-T12433-1mL1 mL * 10 mM (in DMSO)£326.00
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Quantity:
TAR-T12433-10mg10mg£470.00
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Quantity:
TAR-T12433-25mg25mg£707.00
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Quantity:
TAR-T12433-50mg50mg£978.00
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Quantity:
TAR-T12433-100mg100mg£1,291.00
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TAR-T12433-500mg500mg£2,456.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PF-06952229 is a selective inhibitor of TGFβRI. PF-06952229 can be used in studies about the treatment of solid tumors, specifically metastatic breast cancer.
CAS:
1801333-55-0
Formula:
C23H24ClFN4O3
Molecular Weight:
458.91
Pathway:
Stem Cells
Purity:
0.98
SMILES:
O=C(NC(CO)CO)C=1C=NC=CC1NC2=CC(=NC=C2C(C)C)C=3C=C(Cl)C=CC3F
Target:
TGF-beta/Smad

References

1. Flavia Mercer Pernasetti, et al. Combinations of tgfb inhibitors and cdk inhibitors for the treatment of breast cancer. Patent WO2020058820A1.