BMH-21

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TargetMol
Product Code: TAR-T1767
Supplier: TargetMol
CodeSizePrice
TAR-T1767-5mg5mg£99.00
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Quantity:
TAR-T1767-1mL1 mL * 10 mM (in DMSO)£109.00
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Quantity:
TAR-T1767-10mg10mg£115.00
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Quantity:
TAR-T1767-25mg25mg£149.00
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Quantity:
TAR-T1767-50mg50mg£204.00
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Quantity:
TAR-T1767-100mg100mg£302.00
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Quantity:
TAR-T1767-200mg200mg£417.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
CAS:
896705-16-1
Formula:
C21H20N4O2
Molecular Weight:
360.417
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9953
SMILES:
CN(C)CCNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O
Target:
DNA/RNA Synthesis

References

1. Peltonen K, et al. Cancer Cell. 2014, 25(1), 77-90. 2. Colis L, et al. J Med Chem. 2014, 57(11), 4950-4961.