2-PADQZ
| Code | Size | Price |
|---|
| TAR-T19849-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
DPQ is an antiviral compound. DPQ has also been shown to bind to a widened RNA major groove at the internal loop. DPQ acts against the H1N1 and H3N2 strains of influenza A as well as influenza B.
CAS:
60547-97-9
Formula:
C14H19N5O2
Molecular Weight:
289.339
Purity:
0.98
SMILES:
COc1cc2nc(nc(N)c2cc1OC)N1CCNCC1
References
1. Lee MK, Bottini A, Kim M, Bardaro MF Jr, Zhang Z, Pellecchia M, Choi BS, Varani G. A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication. Chem Commun (Camb). 2014 Jan 11;50(3):368-70. doi: 10.1039/c3cc46973e. Epub 2013 Nov 18. Erratum in: Chem Commun (Camb). 2014 Oct 25;50(83):12578. PMID: 24247110; PMCID: PMC3894927.
1. Zhou G, Wang L, Ma Y, Wang L, Zhang Y, Jiang W. Synthesis of a quinazoline derivative: a new ??-adrenoceptor ligand for conjugation to quantum dots to study ??-adrenoceptors in living cells. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5905-9. doi: 10.1016/j.bmcl.2011.07.122. Epub 2011 Aug 10. PubMed PMID: 21875797.
2. Piotrovski? VK, Ve?ko NN, Golovanova IV, Gus'kova TA, Polievktov MK. [Slow elimination of a prazosin metabolite compared to prazosin kinetics after its intravenous administration to rabbits]. Biull Eksp Biol Med. 1987 Jan;103(1):73-5. Russian. PubMed PMID: 3801655.
3. Piotrovskii VK, Veiko NN, Ryabokon OS, Postolnikov SF, Metelitsa VI. Identification of a prazosin metabolite and some preliminary data on its kinetics in hypertensive patients. Eur J Clin Pharmacol. 1984;27(3):275-80. PubMed PMID: 6510454.
4. Althuis TH, Hess HJ. Synthesis and identification of the major metabolites of prazosin formed in dog and rat. J Med Chem. 1977 Jan;20(1):146-9. PubMed PMID: 833813.