Bryonolic acid
| Code | Size | Price |
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| TAR-T19882-5mg | 5mg | £504.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Bryonolic acid is a triterpenoid found in the Cucurbitaceae family of plants. Bryonolic acid has anti-inflammatory and antioxidant activities. It has been found to exhibit antineoplastic activity.
CAS:
24480-45-3
Formula:
C30H48O3
Molecular Weight:
456.711
Purity:
0.98
SMILES:
[H][C@@]12CCC3=C(CC[C@@]4(C)[C@]5([H])C[C@](C)(CC[C@]5(C)CC[C@]34C)C(O)=O)[C@@]1(C)CC[C@H](O)C2(C)C
References
1. Tabata M, Tanaka S, Cho HJ, Uno C, Shimakura J, Ito M, Kamisako W, Honda C. Production of an anti-allergic triterpene bryonolic acid, by plant cell cultures. J Nat Prod. 1993 Feb;56(2):165-74. PubMed PMID: 8463793.
2. Gatbonton-Schwager TN, Letterio JJ, Tochtrop GP. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo. J Nat Prod. 2012 Apr 27;75(4):591-8. doi: 10.1021/np200823p. Epub 2012 Feb 16. PubMed PMID: 22339499; PubMed Central PMCID: PMC4089864.
3. Kondo T, Inoue M, Mizukami H, Ogihara Y. Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica. Biol Pharm Bull. 1995 May;18(5):726-9. PubMed PMID: 7492990.
4. Barker EC, Gatbonton-Schwager TN, Han Y, Clay JE, Letterio JJ, Tochtrop GP. Bryonolic acid: a large-scale isolation and evaluation of heme oxygenase 1 expression in activated macrophages. J Nat Prod. 2010 Jun 25;73(6):1064-8. doi: 10.1021/np1000076. PubMed PMID: 20481554; PubMed Central PMCID: PMC2905313.