(S)-Baclofen
Code | Size | Price |
---|
TAR-T20962-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T20962-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T20962-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
(S)-Baclofen has effects on excitation in the ascending auditory pathway leading to it a potential reagent for the treatment of hyperactive auditory disorders such as hyperacusis and tinnitus.
CAS:
66514-99-6
Formula:
C10H12ClNO2
Molecular Weight:
213.66
Purity:
0.98
SMILES:
NC[C@@H](CC(O)=O)c1ccc(Cl)cc1
References
1. Zheng Y, McPherson K, Smith PF. Effects of early and late treatment with L-baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats. Neuroscience. 2014 Jan 31;258:410-21. doi: 10.1016/j.neuroscience.2013.11.032. Epub 2013 Nov 26. PubMed PMID: 24291770.
2. Zheng Y, Vagal S, McNamara E, Darlington CL, Smith PF. A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats. Neuropharmacology. 2012 Feb;62(2):940-6. doi: 10.1016/j.neuropharm.2011.09.027. Epub 2011 Oct 12. PubMed PMID: 22005094.
3. Fromm GH, Terrence CF. Comparison of L-baclofen and racemic baclofen in trigeminal neuralgia. Neurology. 1987 Nov;37(11):1725-8. PubMed PMID: 3313099.
4. Olpe HR, Demi?ville H, Baltzer V, Bencze WL, Koella WP, Wolf P, Haas HL. The biological activity of d- and l-baclofen (Lioresal). Eur J Pharmacol. 1978 Nov 1;52(1):133-6. PubMed PMID: 214308.