Aglepristone
| Code | Size | Price |
|---|
| TAR-T21132-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Aglepristone is a synthetic steroidal antiprogestogen related to mifepristone and possesses some antiglucocorticoid activity. It is specifically used as an abortifacient in pregnant animals.
CAS:
124478-60-0
Formula:
C29H37NO2
Molecular Weight:
431.62
Purity:
0.98
SMILES:
CC=C/[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C
References
1. Garc?a Mitacek MC, Bonaura MC, Praderio RG, Nu?ez Favre R, de la Sota RL, Stornelli MA. Progesterone and ultrasonographic changes during aglepristone or cloprosternol treatment in queens at 21 to 22 or 35 to 38 days of pregnancy. Theriogenology. 2017 Jan 15;88:106-117. doi: 10.1016/j.theriogenology.2016.09.050. Epub 2016 Oct 6. PubMed PMID: 27865408.
2. ?zalp RG, Yavuz A, Orman A, Seker I, Udum K???k?en D, Ri?vanl? A, Demiral ?O, Wehrend A. Parturition induction in ewes by a progesterone receptor blocker, aglepristone, and subsequent neonatal survival: Preliminary results. Theriogenology. 2017 Jan 1;87:141-147. doi: 10.1016/j.theriogenology.2016.08.016. Epub 2016 Aug 22. PubMed PMID: 27658744.
3. Guil-Luna S, Mill?n Y, De Andres J, Roll?n E, Domingo V, Garc?a-Mac?as J, S?nchez-C?spedes R, Mart?n de Las Mulas J. Prognostic impact of neoadjuvant aglepristone treatment in clinicopathological parameters of progesterone receptor-positive canine mammary carcinomas. Vet Comp Oncol. 2017 Jun;15(2):391-399. doi: 10.1111/vco.12175. Epub 2016 Jan 19. PubMed PMID: 26781329.
4. Gogny A, Fi?ni F. Aglepristone: A review on its clinical use in animals. Theriogenology. 2016 Mar 1;85(4):555-66. doi: 10.1016/j.theriogenology.2015.10.010. Epub 2015 Oct 23. Review. PubMed PMID: 26525399.