CAY10499
Code | Size | Price |
---|
TAR-T22637-5mg | 5mg | £164.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22637-10mg | 10mg | £234.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22637-25mg | 25mg | £428.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CAY10499 is a potent inhibitor of monoglyceride lipase (MGL) and human hormone-sensitive lipase. CAY10499 inhibited MGL-mediated 4-NPA hydrolysis with the IC 50 value of 0.5 ? 0.03 μM. CAY10499 fully inhibited [3H]-AEA hydrolysis by human recombinant FAAH with an IC50 of 76 nM. CAY10499 displaced only 25% and 20% of [3H]-CP-55940-specific binding to the CB1 and CB2 receptors, respectively [1]. CAY10499 potently inhibited the activity of human hormone-sensitive lipase with an IC50 of 90 nM for the recombinant human hormone-sensitive lipase enzyme [1][2].
CAS:
T22637
Formula:
C18H17N3O5
Molecular Weight:
355.3
Purity:
0.98
SMILES:
CC1=CC(N(N=C(O2)OC)C2=O)=CC=C1NC(OCC3=CC=CC=C3)=O