Cularine
| Code | Size | Price |
|---|
| TAR-T23918-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cularine is an isoquinoline alkaloid from the Fumariaceae family. It displays non-specific antispasmodic activity on guinea-pig and human airways.
CAS:
479-39-0
Formula:
C20H23NO4
Molecular Weight:
341.407
Purity:
0.98
SMILES:
[H][C@@]12Cc3cc(OC)c(OC)cc3Oc3c(OC)ccc(CCN1C)c23
References
1. KAMETANI T, FUKUMOTO K. CULARINE AND RELATED COMPOUNDS. IV. THE OXIMINATION AND REDUCTION OF 2,3,6-TRIMETHOXYDIBENZO(B,F)OXEPIN-10(11H)-ONE. Chem Pharm Bull (Tokyo). 1963 Oct;11:1322-5. PubMed PMID: 14075288.
2. KAMETANI T, FUKUMOTO K, MASUKO K. [SYNTHESIS OF CULARINE AND RELATED COMPOUNDS. VII. THE FORMATION OF INDOLE DERIVATIVES. (STUDIES ON THE SYNTHESES OF HETEROCYCLIC COMPOUNDS. XCI.)]. Yakugaku Zasshi. 1963 Nov;83:1052-5. Japanese. PubMed PMID: 14084791.
3. KAMETANI T, FUKUMOTO K, NAKANO T. [Studies on the syntheses of cularine derivatives. I. A synthesis of diphenyl ether by Ullmann reaction and the formation of oxepine nucleus]. Yakugaku Zasshi. 1962 Sep;82:1307-11. Japanese. PubMed PMID: 13962076.
4. D'Ocon P, Blasco R, Candenas L, Ivorra D, L?pez S, Villaverde C, Castedo L, Cortes D. Inhibition of calcium entry induced by cularines and isocrasifoline in uterine smooth muscle. Eur J Pharmacol. 1991 Apr 17;196(2):183-7. PubMed PMID: 1874285.