GSK706
| Code | Size | Price |
|---|
| TAR-T24114-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24114-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24114-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
GSK706 is a novel effective agonist of the GPR119.
CAS:
1032824-43-3
Formula:
C23H29N5O4S
Molecular Weight:
471.58
Purity:
0.98
SMILES:
CC(C)c1noc(n1)N1CCC(CC1)[C@H](C)Oc1cnc(cn1)-c1ccc(cc1)S(C)(=O)=O
References
1. Taylor A, Rothstein D, Rudd CE. Small-Molecule Inhibition of PD-1 Transcription Is an Effective Alternative to Antibody Blockade in Cancer Therapy. Cancer Res. 2018 Feb 1;78(3):706-717. doi: 10.1158/0008-5472.CAN-17-0491. Epub 2017 Oct 20. PubMed PMID: 29055015.
2. Abberley L. Outsourcing of bioanalysis at GSK: a hybrid approach with a robust support model. Bioanalysis. 2017 Aug;9(15):1139-1144. doi: 10.4155/bio-2017-0062. Epub 2017 Aug 1. PubMed PMID: 28762760.
3. Zafar A, Hasan R, Nizamuddin S, Mahmood N, Mukhtar S, Ali F, Morrissey I, Barker K, Torumkuney D. Antibiotic susceptibility in Streptococcus pneumoniae, Haemophilus influenzae and Streptococcus pyogenes in Pakistan: a review of results from the Survey of Antibiotic Resistance (SOAR) 2002-15. J Antimicrob Chemother. 2016 May;71 Suppl 1:i103-9. doi: 10.1093/jac/dkw076. PubMed PMID: 27048578; PubMed Central PMCID: PMC4890355.
4. Park SJ, Jin ML, An HK, Kim KS, Ko MJ, Kim CM, Choi YW, Lee YC. Emodin induces neurite outgrowth through PI3K/Akt/GSK-3?-mediated signaling pathways in Neuro2a cells. Neurosci Lett. 2015 Feb 19;588:101-7. doi: 10.1016/j.neulet.2015.01.001. Epub 2015 Jan 3. PubMed PMID: 25562207.