L 8412

TargetMol
Product Code: TAR-T24364
Supplier: TargetMol
CodeSizePrice
TAR-T24364-5mg5mg£850.00
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Quantity:
TAR-T24364-50mg50mg£1,661.00
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Quantity:
TAR-T24364-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
L 8412 is an anti-adrenergic agent.
CAS:
50602-48-7
Formula:
C30H42ClNO3
Molecular Weight:
500.12
Purity:
0.98
SMILES:
Cl.CCCCN(CCCC)CCCOc1c(C)cc(cc1C)C(=O)c1c(CC)oc2ccccc12

References

1. Sekiguchi H, Kuroyanagi T, Rhainds D, Kobayashi K, Kobayashi Y, Ohno H, Heveker N, Akaji K, Fujii N, Oishi S. Structure-Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3). J Med Chem. 2018 Apr 26;61(8):3745-3751. doi: 10.1021/acs.jmedchem.8b00336. Epub 2018 Apr 12. PubMed PMID: 29608300. 2. De Sousa SMC, Sheriff N, Tran CH, Menzies AM, Tsang VHM, Long GV, Tonks KTT. Fall in thyroid stimulating hormone (TSH) may be an early marker of ipilimumab-induced hypophysitis. Pituitary. 2018 Jun;21(3):274-282. doi: 10.1007/s11102-018-0866-6. PubMed PMID: 29380110. 3. Shigemi Z, Manabe K, Hara N, Baba Y, Hosokawa K, Kagawa H, Watanabe T, Fujimuro M. Methylseleninic acid and sodium selenite induce severe ER stress and subsequent apoptosis through UPR activation in PEL cells. Chem Biol Interact. 2017 Mar 25;266:28-37. doi: 10.1016/j.cbi.2017.01.027. Epub 2017 Feb 1. PubMed PMID: 28161410. 4. Sharpe RA, Thornton CR, Tyrrell J, Nikolaou V, Osborne NJ. Variable risk of atopic disease due to indoor fungal exposure in NHANES 2005-2006. Clin Exp Allergy. 2015 Oct;45(10):1566-78. doi: 10.1111/cea.12549. PubMed PMID: 25845975.