SA-16
| Code | Size | Price |
|---|
| TAR-T24753-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SA-16 is a potent dual inhibitor of PDK1 and Aurora kinase.
CAS:
1919884-11-9
Formula:
C33H24F2N6O4
Molecular Weight:
606.59
Purity:
0.98
SMILES:
Fc1ccc(Cn2cccc(C(=O)N[C@@H](C(=O)Nc3ccc4NC(=O)C(=C/c5cnc[nH]5)c4c3)c3ccccc3)c2=O)cc1F
References
1. Daniele S, Sestito S, Pietrobono D, Giacomelli C, Chiellini G, Di Maio D, Marinelli L, Novellino E, Martini C, Rapposelli S. Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells. ACS Chem Neurosci. 2017 Jan 18;8(1):100-114. doi: 10.1021/acschemneuro.6b00251. Epub 2016 Nov 10. PubMed PMID: 27797168.
2. Giraud K, Pontin M, Sharples LD, Fletcher P, Dalgleish T, Eden A, Jenkins DP, Vuylsteke A. Use of a Structured Mirrors Intervention Does Not Reduce Delirium Incidence But May Improve Factual Memory Encoding in Cardiac Surgical ICU Patients Aged Over 70 Years: A Pilot Time-Cluster Randomized Controlled Trial. Front Aging Neurosci. 2016 Sep 28;8:228. eCollection 2016. PubMed PMID: 27733826; PubMed Central PMCID: PMC5039170.
3. Dabul AN, Kos VN, Gilmore MS, Camargo IL. Draft Genome Sequence of Methicillin-Resistant Staphylococcus aureus Strain SA16, Representative of an Endemic Clone from a Brazilian Hospital. Genome Announc. 2013 Sep 19;1(5). pii: e00754-13. doi: 10.1128/genomeA.00754-13. PubMed PMID: 24051324; PubMed Central PMCID: PMC3778207.
4. Asiegbu FO, Abu S, Stenlid J, Johansson M. Sequence polymorphism and molecular characterization of laccase genes of the conifer pathogen Heterobasidion annosum. Mycol Res. 2004 Feb;108(Pt 2):136-48. PubMed PMID: 15119350.