Aklavin
| Code | Size | Price |
|---|
| TAR-T25014-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Aklavin is an antibiotic prepared from culture liquids of streptomycete (A 1129) that has antiphage activity.
CAS:
60504-57-6
Formula:
C30H35NO10
Molecular Weight:
569.61
Purity:
0.98
SMILES:
c1c(c2c(cc1)C(=O)c1c(c(c3c(c1)[C@@H](C(=O)OC)[C@@](O)(CC)C[C@@H]3O[C@H]1C[C@@H]([C@@H]([C@@H](O1)C)O)N(C)C)O)C2=O)O
References
1. Dickens ML, Strohl WR. Isolation and characterization of a gene from Streptomyces sp. strain C5 that confers the ability to convert daunomycin to doxorubicin on Streptomyces lividans TK24. J Bacteriol. 1996 Jun;178(11):3389-95. PubMed PMID: 8655530; PubMed Central PMCID: PMC178102.
2. Sohda M, Fujiwara K, Saikusa H, Kitagawa T, Nakamura N, Hara K, Tone H. Sensitive enzyme immunoassay for the quantification of aclacinomycin A using beta-D-galactosidase as a label. Cancer Chemother Pharmacol. 1985;14(1):53-8. PubMed PMID: 3917377.
3. Matsuzawa Y, Kiyosaki T, Oki T, Takeuchi T, Umezawa H. Radioimmunoassay for aclacinomycin A. Gan. 1982 Apr;73(2):229-33. PubMed PMID: 6956531.
4. Oki T, Yoshimoto A, Matsuzawa Y, Takeuchi T, Umezawa H. Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. I. Glycosidation of various anthracyclinones by an aclacinomycin-negative mutant and biosynthesis of aclacinomycins from aklavinone. J Antibiot (Tokyo). 1980 Nov;33(11):1331-40. PubMed PMID: 6941952.