Chlorambucyl-proline
Code | Size | Price |
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TAR-T25238-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25238-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25238-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Chlorambucyl-proline is a chlorambucil derivative of L-proline. It is an inhibitor of bovine lung angiotensin I-converting enzyme.
CAS:
81050-71-7
Formula:
C19H26Cl2N2O3
Molecular Weight:
401.33
Purity:
0.98
SMILES:
OC(=O)[C@@H]1CCCN1C(=O)CCCc1ccc(cc1)N(CCCl)CCCl
References
1. Harris RB, Wilson IB. Irreversible inhibition of bovine lung angiotensin I-converting enzyme with p-[N,N-bis(chloroethyl)amino]phenylbutyric acid (chlorambucil) and chlorambucyl L-proline and with evidence that an active site carboxyl group is labeled. J Biol Chem. 1982 Jan 25;257(2):811-5. PubMed PMID: 6274865.
2. Bielawska A, Bielawski K, Pa?ka J. Prolidase as a prodrug converting enzyme I. Synthesis of proline analogue of chlorambucil and its susceptibility to the action of prolidase. Rocz Akad Med Bialymst. 1997;42(1):148-55. PubMed PMID: 9581474.