Iomazenil
| Code | Size | Price |
|---|
| TAR-T25537-5mg | 5mg | £1,171.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25537-50mg | 50mg | £2,303.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25537-100mg | 100mg | £3,042.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Iomazenil is an antagonist and partial inverse agonist of benzodiazepine and potential therapy for alcohol abuse.
CAS:
127985-21-1
Formula:
C15H14IN3O3
Molecular Weight:
411.199
Purity:
0.98
SMILES:
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1c(I)cccc-21
References
1. Taguchi Y, Takashima S, Noguchi K, Tanaka K. Findings of 123I-iomazenil SPECT during and after stroke-like episodes in a patient with MELAS. Clin Nucl Med. 2014 Jun;39(6):e334-5. doi: 10.1097/RLU.0b013e318299610f. PubMed PMID: 24097000.
2. Nagamitsu S, Yamashita Y, Tanigawa H, Chiba H, Kaida H, Ishibashi M, Kakuma T, Croarkin PE, Matsuishi T. Upregulated GABA Inhibitory Function in ADHD Children with Child Behavior Checklist-Dysregulation Profile: 123I-Iomazenil SPECT Study. Front Psychiatry. 2015 Jun 2;6:84. doi: 10.3389/fpsyt.2015.00084. eCollection 2015. PubMed PMID: 26082729; PubMed Central PMCID: PMC4451796.
3. Nagamitsu S, Sakurai R, Matsuoka M, Chiba H, Ozono S, Tanigawa H, Yamashita Y, Kaida H, Ishibashi M, Kakuma T, Croarkin PE, Matsuishi T. Altered SPECT (123)I-iomazenil Binding in the Cingulate Cortex of Children with Anorexia Nervosa. Front Psychiatry. 2016 Feb 16;7:16. doi: 10.3389/fpsyt.2016.00016. eCollection 2016. PubMed PMID: 26909048; PubMed Central PMCID: PMC4754452.
4. Tsartsalis S, Moulin-Sallanon M, Dumas N, Tournier BB, Ghezzi C, Charnay Y, Ginovart N, Millet P. Quantification of GABAA receptors in the rat brain with [(123)I]Iomazenil SPECT from factor analysis-denoised images. Nucl Med Biol. 2014 Feb;41(2):186-95. doi: 10.1016/j.nucmedbio.2013.11.008. Epub 2013 Nov 28. PubMed PMID: 24405841.