IRL-3630
| Code | Size | Price |
|---|
| TAR-T25541-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
IRL 3460 is an enantiomer.
CAS:
173189-01-0
Formula:
C31H40N4O6S
Molecular Weight:
596.74
Purity:
0.98
SMILES:
CCCCS(=O)(=O)N([C@@H](C(C)C)C(N)=O)C(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1
References
1. Sakaki J, Murata T, Yuumoto Y, Nakamura I, Hayakawa K. Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2247-52. PubMed PMID: 9873522.
2. Sakaki J, Murata T, Yuumoto Y, Nakamura I, Trueh T, Pitterna T, Iwasaki G, Oda K, Yamamura T, Hayakawa K. Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2241-6. PubMed PMID: 9873521.
3. Makatani M, Fujitani Y, Takimoto M, Oda K, Sasaki Y, Hori S, Inui T, Sakaki J, Okada T, Hoshiko K, Yamamura T. Effect of a novel bifunctional endothelin receptor antagonist, IRL 3630A, on guinea pig respiratory mechanics. Eur J Pharmacol. 2000 Oct 6;406(1):139-47. PubMed PMID: 11011045.