Jmv 320
| Code | Size | Price |
|---|
| TAR-T25552-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Jmv 320 is a highly selective gastrin receptor and cholecystokinin receptor antagonist. It is a cyclic cholecystokinin-8 analog in which positions 28 and 31 have been replaced by Lys, with their side chains bridged by a succinic moiety.
CAS:
130582-10-4
Formula:
C53H67N11O13
Molecular Weight:
1066.183
Purity:
0.98
SMILES:
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCCNC(=O)CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
References
1. Witte DG, Nadzan AM, Martinez J, Rodriguez M, Lin CW. Characterization of the novel CCK analogs JMV-180, JMV-320, and JMV-332 in H345 cells. Peptides. 1992 Nov-Dec;13(6):1227-32. PubMed PMID: 1337381.
2. Hadjiivanova C, Kehayov R, Petkov VV, Amblard M, Martinez J. Behavioral effects of the cyclic cholecystokinin peptide analogue JMV-320. Peptides. 1995;16(5):815-9. PubMed PMID: 7479320.
3. Ishizuka J, Martinez J, Townsend CM Jr, Thompson JC. The effect of gastrin on growth of human stomach cancer cells. Ann Surg. 1992 May;215(5):528-34. PubMed PMID: 1616389; PubMed Central PMCID: PMC1242491.
4. Lignon MF, Bernad N, Martinez J. Cholecystokinin receptors in cells of the immune system. Ann N Y Acad Sci. 1994 Mar 23;713:334-7. PubMed PMID: 8185180.