LRH-1 Inhibitor-3
| Code | Size | Price |
|---|
| TAR-T25758-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25758-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25758-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LRH-1 Inhibitor-3 is the first small molecule LRH-1 activity antagonist.
CAS:
1185410-60-9
Formula:
C23H25N3O2
Molecular Weight:
375.472
Purity:
0.98
SMILES:
CC(=O)c1cccc(c1)-c1cccc(c1)-c1ccn(CCN2CCOCC2)n1
References
1. Jiang Y, Zhao Y, Chen S, Chen L, Li C, Zhou X. Regulation by FSH of the dynamic expression of retinol-binding protein 4 in the mouse ovary. Reprod Biol Endocrinol. 2018 Mar 20;16(1):25. doi: 10.1186/s12958-018-0348-8. PubMed PMID: 29558965; PubMed Central PMCID: PMC5859637.
2. Salmenkari H, Holappa M, Forsgard RA, Korpela R, Vapaatalo H. Orally administered angiotensin-converting enzyme-inhibitors captopril and isoleucine-proline-proline have distinct effects on local renin-angiotensin system and corticosterone synthesis in dextran sulfate sodium-induced colitis in mice. J Physiol Pharmacol. 2017 Jun;68(3):355-362. PubMed PMID: 28820392.
3. Yang FM, Feng SJ, Lai TC, Hu MC. A calreticulin-dependent nuclear export signal is involved in the regulation of liver receptor homologue-1 protein folding. Biochem J. 2015 Oct 15;471(2):199-209. doi: 10.1042/BJ20150252. Epub 2015 Aug 12. PubMed PMID: 26268559.
4. Bianco S, Jangal M, Garneau D, G?vry N. LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression. Oncogene. 2015 Aug 20;34(34):4509-18. doi: 10.1038/onc.2014.382. Epub 2014 Dec 1. PubMed PMID: 25435372.