Ruboxyl
| Code | Size | Price |
|---|
| TAR-T26161-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ruboxyl, a nitroxylated analog of daunorubicin, is an anthracycline antibiotic.
CAS:
80214-88-6
Formula:
C36H47ClN4O10
Molecular Weight:
731.24
Purity:
0.98
SMILES:
Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=N/N=C1CC(C)(C)N(O)C(C)(C)C1
References
1. Kotelnikov AI, Rybkin AY, Khakina EA, Kornev AB, Barinov AV, Goryachev NS, Ivanchikhina AV, Peregudov AS, Martynenko VM, Troshin PA. Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy. Org Biomol Chem. 2013 Jul 14;11(26):4397-404. doi: 10.1039/c3ob40136g. Epub 2013 May 28. PubMed PMID: 23712714.
2. Seminara P, Franchi F, Konovalova N, Pioli C, Rossetti R, Tubani L, Doria G, Rossi Fanelli F. Activity of a nitroxylated analog of daunorubicin, ruboxyl, in B-lymphoproliferative disorders. Acta Haematol. 2001;105(2):77-82. PubMed PMID: 11408708.
3. Konovalova NP, Volkova LM, Codacci-Pisanelli D, Seminara P, Franchi F. [Effect of Ruboxyl (nitroxyl derivative of daunorubicin) on hepatic metastases of colorectal carcinoma]. Vopr Onkol. 2000;46(4):438-41. Russian. PubMed PMID: 11147420.
4. Rapoport NY, Herron JN, Pitt WG, Pitina L. Micellar delivery of doxorubicin and its paramagnetic analog, ruboxyl, to HL-60 cells: effect of micelle structure and ultrasound on the intracellular drug uptake. J Control Release. 1999 Mar 29;58(2):153-62. PubMed PMID: 10053188.