VU0366248

1. Identification of Specific Ligand?Receptor Interactions That Govern Binding and Cooperativity of Diverse Modulators to a Common Metabotropic Glutamate Receptor 5 Allosteric Site Karen J. Gregory, Elizabeth D. Nguyen, Chrysa Malosh, Jeffrey L. Mendenhall, Jessica Z. Zic, Brittney S. Bates, Meredith J. Noetzel, Emma F. Squire, Eric M. Turner, Jerri M. Rook, Kyle A. Emmitte, Shaun R. Stauffer, Craig W. Lindsley, Jens Meiler, P. Jeffrey Conn ACS Chem Neurosci. 2014 Apr 16; 5(4): 282?295. Published online 2014 Feb 16. doi: 10.1021/cn400225x PMCID: PMC3990945 2. Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships Karen J. Gregory, Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson, Shaun R. Stauffer, Alice L. Rodriguez, Kyle A. Emmitte, Ya Zhou, Aspen C. Chun, Andrew S. Felts, Brian A. Chauder, Craig W. Lindsley, Colleen M. Niswender, P. Jeffrey Conn Mol Pharmacol. 2012 Nov; 82(5): 860?875. doi: 10.1124/mol.112.080531 PMCID: PMC3477233 3. VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy Hilary Highfield Nickols, Joannes P. Yuh, Karen J. Gregory, Ryan D. Morrison, Brittney S. Bates, Shaun R. Stauffer, Kyle A. Emmitte, Michael Bubser, Weimin Peng, Michael T. Nedelcovych, Analisa Thompson, Xiaohui Lv, Zixiu Xiang, J. Scott Daniels, Colleen M. Niswender, Craig W. Lindsley, Carrie K. Jones, P. Jeffrey Conn J Pharmacol Exp Ther. 2016 Jan; 356(1): 123?136. Published online 2016 Jan. doi: 10.1124/jpet.115.226597 PMCID: PMC4702078 4. Molecular Insights into Metabotropic Glutamate Receptor Allosteric Modulation Karen J. Gregory, P. Jeffrey Conn Mol Pharmacol. 2015 Jul; 88(1): 188?202. Published online 2015 Jul. doi: 10.1124/mol.114.097220 PMCID: PMC4468636