Acanthifolicin
| Code | Size | Price |
|---|
| TAR-T26544-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Acanthifolicin, an okadaic acid derivative, has been shown top inhibit protein phosphatase 1 with an IC50= 20 nM (similar to that of okadaic acid at 19 nM).
CAS:
77739-71-0
Formula:
C44H68O13S
Molecular Weight:
837.08
Purity:
0.98
SMILES:
C[C@@H](C[C@@H](O)[C@@H]1O[C@@H]2CC[C@@]3(CC[C@@H](O3)C=C[C@@H](C)[C@@H]3C[C@@]4(C)S[C@@H]4[C@]4(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]4O)O3)O[C@H]2[C@H](O)C1=C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C
References
1. Holmes CF, Luu HA, Carrier F, Schmitz FJ. Inhibition of protein phosphatases-1 and -2A with acanthifolicin. Comparison with diarrhetic shellfish toxins and identification of a region on okadaic acid important for phosphatase inhibition. FEBS Lett. 1990 Sep 17;270(1-2):216-8. PubMed PMID: 2171991.