Acaterin
Code | Size | Price |
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TAR-T26548-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26548-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26548-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Acaterin, an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), inhibits synthesis of cholesteryl ester in macrophage J774.
CAS:
144398-20-9
Formula:
C13H22O3
Molecular Weight:
226.316
Purity:
0.98
SMILES:
CCCCCCCC(O)C1=CC(C)OC1=O
References
1. Naganuma S, Sakai K, Hasumi K, Endo A. Acaterin, a novel inhibitor of acyl-CoA: cholesterol acyltransferase produced by Pseudomonas sp. A92. J Antibiot (Tokyo). 1992 Aug;45(8):1216-21. PubMed PMID: 1399841.
2. Nakano S, Sakane W, Oinaka H, Fujimoto Y. Biosynthesis of acaterin: mechanism of the reaction catalyzed by dehydroacaterin reductase. Bioorg Med Chem. 2006 Sep 15;14(18):6404-8. Epub 2006 Jun 9. PubMed PMID: 16765052.
3. Sekiyama Y, Fujimoto Y, Hasumi K, Endo A. Biosynthesis of acaterin: coupling of C(5) unit with octanoate. J Org Chem. 2001 Aug 24;66(17):5649-54. PubMed PMID: 11511235.
4. Hatano E, Hashidoko Y, Deora A, Fukushi Y, Tahara S. Isolation and structure elucidation of Peronosporomycetes hyphal branching-inducing factors produced by Pseudomonas jessenii EC-S101. Biosci Biotechnol Biochem. 2007 Jun;71(6):1601-5. PubMed PMID: 17587701.