ARC-239
Code | Size | Price |
---|
TAR-T26651-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26651-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
ARC-239 is an agonist of α2-adrenergic receptor.
CAS:
67339-62-2
Formula:
C25H30N2O3
Molecular Weight:
406.526
Purity:
0.98
SMILES:
COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1
References
1. Yamanaka D, Kawano T, Nishigaki A, Aoyama B, Tateiwa H, Shigematsu-Locatelli M, Locatelli FM, Yokoyama M. Preventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats. J Anesth. 2016 Oct 13. [Epub ahead of print] PubMed PMID: 27738803.
2. Wang Y, Wu S, Yu X, Zhou S, Ge M, Chi X, Cai J. Dexmedetomidine Protects Rat Liver against Ischemia-Reperfusion Injury Partly by the ?2A-Adrenoceptor Subtype and the Mechanism Is Associated with the TLR4/NF-?B Pathway. Int J Mol Sci. 2016 Jun 23;17(7). pii: E995. doi: 10.3390/ijms17070995. PubMed PMID: 27347929; PubMed Central PMCID: PMC4964371.
3. Hajagos-T?th J, B?ta J, Ducza E, Samavati R, Borsodi A, Benyhe S, G?sp?r R. The effects of progesterone on the alpha2-adrenergic receptor subtypes in late-pregnant uterine contractions in vitro. Reprod Biol Endocrinol. 2016 Jun 14;14(1):33. doi: 10.1186/s12958-016-0166-9. PubMed PMID: 27301276; PubMed Central PMCID: PMC4908715.
4. Hajagos-Toth J, Bota J, Ducza E, Csanyi A, Tiszai Z, Borsodi A, Samavati R, Benyhe S, Gaspar R. The effects of estrogen on the ?2-adrenergic receptor subtypes in rat uterine function in late pregnancy in vitro. Croat Med J. 2016 Apr 23;57(2):100-9. PubMed PMID: 27106352; PubMed Central PMCID: PMC4856191.