BF-1
| Code | Size | Price |
|---|
| TAR-T26781-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BF-1 is a 5-Hydroxytryptamine receptor 2B antagonist. BF-1 was tested as potential migraine prophylactic drug by blocking BW723C86 (5-((thiophen-2-yl)methoxy)-α-methyltryptamine) or meta-chlorophenylpiperazine (mCPP) induced neurogenic dural plasma protein extravasation in a guinea pig model that may resemble a migraine attack.
CAS:
518980-66-0
Formula:
C22H25NO2S
Molecular Weight:
367.51
Purity:
0.98
SMILES:
CCOc1ccc2C(=C3CCN(C)CC3)c3c(OC)cccc3Sc2c1
References
1. Schmitz B, Ullmer C, Segelcke D, Gwarek M, Zhu XR, L?bbert H. BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs. Eur J Pharmacol. 2015 Mar 15;751:73-80. doi: 10.1016/j.ejphar.2015.01.043. PubMed PMID: 25666387.