Bharangin
| Code | Size | Price |
|---|
| TAR-T26790-5mg | 5mg | £1,171.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26790-50mg | 50mg | £2,303.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26790-100mg | 100mg | £3,042.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Bharangin is a inhibitor of penicillinase enzyme in E coli.
CAS:
72711-84-3
Formula:
C20H24O4
Molecular Weight:
328.408
Purity:
0.98
SMILES:
CC(C)C1=CC2=CC=C3C(C)(C)CC(=O)O[C@@]3(C)CC2=C(O)C1=O
References
1. Murthy MM, Subramanyam M, Giridhar KV, Jetty A. Antimicrobial activities of bharangin from Premna herbaceae Roxb. and bharangin monoacetate. J Ethnopharmacol. 2006 Mar 8;104(1-2):290-2. Epub 2005 Oct 27. PubMed PMID: 16257159.
2. Sathish T, Brahmaiah P, Sathya K, Bhojaraju P, Naik NG, Kezia D, Prakasam RS. A novel RP-HPLC method for the determination of bharangin in Ghantu bharangi crude extracts. Pak J Pharm Sci. 2009 Jan;22(1):68-73. PubMed PMID: 19168424.
3. Gupta SC, Kannappan R, Kim J, Rahman GM, Francis SK, Raveendran R, Nair MS, Das J, Aggarwal BB. Bharangin, a diterpenoid quinonemethide, abolishes constitutive and inducible nuclear factor-?B (NF-?B) activation by modifying p65 on cysteine 38 residue and reducing inhibitor of nuclear factor-?B ? kinase activation, leading to suppression of NF-?B-regulated gene expression and sensitization of tumor cells to chemotherapeutic agents. Mol Pharmacol. 2011 Nov;80(5):769-81. doi: 10.1124/mol.111.073122. Epub 2011 Jul 27. PubMed PMID: 21795584; PubMed Central PMCID: PMC3198918.
4. Lakshmi VV, Sridhar P, Polasa H. Loss of plasmid linked antibiotic resistance in Escherichia coli on treatment with some phenolic compounds. FEMS Microbiol Lett. 1989 Feb;57(3):275-8. PubMed PMID: 2656388.