CL-184005
Code | Size | Price |
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TAR-T27035-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27035-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27035-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CL-184005 is a platelet activating factor (PAF) inhibitor. CL-184005 interferes with tumor necrosis factor synthesis. CL-184005 also dreases Spleen-associated tumor necrosis factor protein.
CAS:
140466-18-8
Formula:
C33H46NO7PS
Molecular Weight:
631.76
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCOc1cccc(OP([O-])(=O)Oc2cccc(C[n+]3csc(C)c3)c2)c1C(=O)OC
References
1. Negro Alvarez JM, Miralles L?pez JC, Ortiz Mart?nez JL, Abell?n Alem?n A, Rubio del Barrio R. Platelet-activating factor antagonists. Allergol Immunopathol (Madr). 1997 Sep-Oct;25(5):249-58. Review. PubMed PMID: 9395010.
2. Chen J, Giris N. Species differences in PAF receptor binding in the lungs between hamster and guinea pig. J Lipid Mediat Cell Signal. 1997 Jun;16(2):63-74. PubMed PMID: 9172049.
3. Dirkes K, Harris BH, Connolly RJ, Schwaitzberg SD, Dinarello CA, Gelfand JA. Platelet activating factor-antagonist improves survival in experimental staphylococcal septicemia. J Pediatr Surg. 1994 Aug;29(8):1055-7; discussion 1057-8. PubMed PMID: 7965505.
4. DeJoy SQ, Jeyaseelan R Sr, Torley LW, Pickett WC, Wissner A, Wick MM, Oronsky AL, Kerwar SS. Effect of CL 184,005, a platelet-activating factor antagonist in a murine model of Staphylococcus aureus-induced gram-positive sepsis. J Infect Dis. 1994 Jan;169(1):150-6. PubMed PMID: 8277176.