Crisnatol mesylate
Code | Size | Price |
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TAR-T27085-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27085-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27085-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.
CAS:
96389-69-4
Formula:
C24H25NO4S
Molecular Weight:
423.53
Purity:
0.98
SMILES:
CC(CO)(COS(C)(=O)=O)NCc1cc2c3ccccc3ccc2c2ccccc12
References
1. Villalona-Calero MA, Petit T, Kuhn J, Cobb P, Kraynak M, Eckhardt SG, Drengler R, Simmons C, Santabarbara P, Von Hoff DD, Rowinsky EK. A phase I and pharmacological study of protracted infusions of crisnatol mesylate in patients with solid malignancies. Clin Cancer Res. 1999 Nov;5(11):3369-78. PubMed PMID: 10589747.
2. Dorr RT, Bellamy W, Liddil JD, Baker A, Bair KW. Correlation of cytotoxicity and protein-associated DNA strand breaks for 2-(arylmethylamino)-1,3-propanediols. Anticancer Drug Des. 1998 Oct;13(7):825-35. PubMed PMID: 9807165.
3. New P, Vokes E, Rogers L, Bazan C, Hohneker J, Eble M, Vilk P. Long-term response to crisnatol mesylate in patients with glioma. Invest New Drugs. 1997;15(4):343-52. PubMed PMID: 9547677.
4. Bailey H, Kohler P, Tuttle R, Carbone PP, Hohneker JA, Clendeninn NJ, Wilding G. Phase I evaluation of 773U82-HCl in a two-hour infusion repeated daily for three days. Invest New Drugs. 1992 Nov;10(4):279-87. PubMed PMID: 1487401.